Who:   VIPs and those who can at least play it for one great night in Vegas.
What:   Set inside the luxe Wynn Hotel, Tryst is equally opulent. The dance floor and main lounge have a view of the hotel's towering 90-ft waterfall ("stunning" is an understatement). Three bars, go-go dancers, poles and cave-like VIP areas surround the outdoor lagoon. Locals consider Thursday nights to be "Tryst" night, so reserve your table then.
Why:   Whoever came up with the term "nightlife" had this place in mind.